Babbette LaMarca Selected Research

17-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)

10/2020	17-Hydroxyprogesterone caproate improves hypertension and renal endothelin-1 in response to sFlt-1 induced hypertension in pregnant rats.
12/2017	Continued Investigation Into 17-OHPC: Results From the Preclinical RUPP Rat Model of Preeclampsia.
1/2015	17-hydroxyprogesterone caproate significantly improves clinical characteristics of preeclampsia in the reduced uterine perfusion pressure rat model.
9/2009	17-Hydroxyprogesterone blunts the hypertensive response associated with reductions in uterine perfusion pressure in pregnant rats.

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Babbette LaMarca Research Topics

Disease

49	Hypertension (High Blood Pressure) 04/2024 - 08/2006
47	Pre-Eclampsia (Preeclampsia) 04/2024 - 10/2009
21	Ischemia 02/2024 - 12/2008
10	Inflammation (Inflammations) 04/2024 - 04/2011
5	Fetal Weight 10/2021 - 12/2017
4	Mitochondrial Diseases (Mitochondrial Disease) 10/2021 - 01/2018
2	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2021 - 12/2016
2	Premature Birth (Birth, Premature) 10/2020 - 01/2015
2	Hypoxia (Hypoxemia) 10/2018 - 09/2014
2	Leiomyoma (Uterine Fibroids) 10/2018 - 09/2014
2	Disease Progression 08/2017 - 10/2014
2	Eclampsia 01/2015 - 06/2013
2	Autoimmune Diseases (Autoimmune Disease) 10/2014 - 04/2011
2	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 07/2011 - 06/2007
1	Birth Weight (Birth Weights) 02/2024
1	Spontaneous Abortion (Miscarriage) 01/2021
1	Brain Edema (Cerebral Edema) 11/2020
1	Fetal Death 01/2018
1	HELLP Syndrome 01/2015
1	Hemorrhagic Stroke 01/2015
1	Hemolysis 01/2015
1	Renal Insufficiency (Renal Failure) 01/2015
1	Pulmonary Edema 01/2015
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 10/2014
1	Fibrosis (Cirrhosis) 10/2014
1	Uterine Hemorrhage (Uterine Bleeding) 09/2014
1	Neuroinflammatory Diseases 01/2014
1	Posterior Leukoencephalopathy Syndrome 06/2013
1	Proteinuria 06/2012

Drug/Important Bio-Agent (IBA)

31	AutoantibodiesIBA 04/2024 - 12/2008
17	Angiotensin IIIBA 04/2024 - 12/2008
17	CytokinesIBA 01/2023 - 12/2008
14	Endothelin-1 (Endothelin 1)IBA 01/2022 - 10/2009
11	Type 1 Angiotensin ReceptorIBA 01/2023 - 10/2009
10	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 07/2011
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 12/2008
9	Endothelins (Endothelin)IBA 10/2018 - 08/2006
7	Tyrosine (L-Tyrosine)FDA Link 01/2022 - 01/2012
4	Interleukin-17 (Interleukin 17)IBA 04/2024 - 08/2012
4	Progesterone FDA LinkGeneric 10/2021 - 08/2014
4	hexanoic acid (hexanoate)IBA 10/2020 - 09/2009
4	17-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)IBA 10/2020 - 09/2009
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2016 - 10/2009
3	Rituximab (Mabthera)FDA Link 02/2024 - 04/2011
3	Peptides (Polypeptides)IBA 11/2022 - 06/2012
3	Interleukin-10 (Interleukin 10)IBA 01/2019 - 01/2015
3	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 01/2018 - 08/2010
3	Interleukin-6 (Interleukin 6)IBA 12/2016 - 09/2009
2	Vasoconstrictor AgentsIBA 01/2023 - 01/2021
2	blocking factorIBA 10/2021 - 01/2021
2	Interleukin-2 (IL2)IBA 10/2021 - 01/2021
2	Abatacept (Orencia)FDA Link 01/2021 - 06/2013
2	Proteins (Proteins, Gene)FDA Link 11/2020 - 01/2018
2	Interleukin-4 (Interleukin 4)IBA 01/2019 - 01/2019
2	tempolIBA 01/2018 - 08/2012
2	Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric 08/2017 - 01/2014
2	Vitamin D FDA LinkGeneric 01/2017 - 02/2016
2	EndoglinIBA 04/2013 - 08/2010
1	Complement System Proteins (Complement)IBA 01/2023
1	salicylhydroxamic acid (SHAM)IBA 11/2022
1	Amino Acids FDA Link 11/2022
1	Basiliximab FDA Link 01/2021
1	Etanercept (Enbrel)FDA Link 11/2020
1	Oxygen (Dioxygen)IBA 10/2018
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 10/2018
1	Cysteine (L-Cysteine)FDA Link 10/2018
1	Arachidonic Acid (Vitamin F)IBA 01/2018
1	20-hydroxy-5,8,11,14-eicosatetraenoic acidIBA 01/2018
1	Hydroxyeicosatetraenoic Acids (HETE)IBA 01/2018
1	Cytochrome P-450 CYP4A (Alkane 1 Monooxygenase)IBA 01/2018
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2018
1	Monoclonal AntibodiesIBA 11/2017
1	Hydralazine (Apresoline)FDA LinkGeneric 08/2017
1	Labetalol (Normodyne)FDA LinkGeneric 08/2017
1	human serelaxin proteinIBA 12/2016
1	2- (2- (1- phenyl- 4- piperazynyl)ethyl)- 1,2,3,4- tetrahydro- beta- carboline- 1- spiro- 4'- N'- benzylpiperidineIBA 12/2016
1	RelaxinIBA 12/2016
1	Inflammation MediatorsIBA 01/2016
1	CD40 Ligand (CD40L)IBA 11/2015
1	LigandsIBA 11/2015
1	EnzymesIBA 01/2015
1	NADP (NADPH)IBA 11/2014
1	acetovanillone (apocynin)IBA 11/2014
1	Peroxidase (Myeloperoxidase)IBA 11/2014
1	AlbuminsIBA 10/2014
1	Lipocalin-2IBA 10/2014
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 10/2014
1	DNA (Deoxyribonucleic Acid)IBA 10/2014
1	Messenger RNA (mRNA)IBA 09/2014
1	ReninIBA 08/2014
1	InterleukinsIBA 08/2014
1	AntibodiesIBA 08/2014
1	CholesterolIBA 01/2014
1	Drinking WaterIBA 07/2012
1	AtrasentanIBA 07/2012
1	SaltsIBA 08/2011
1	SodiumIBA 08/2011

Therapy/Procedure

5	Therapeutics 01/2023 - 06/2013
2	Hysterectomy 10/2018 - 09/2014
1	Critical Care (Surgical Intensive Care) 06/2013